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eGFR 55: What It Means (CKD Stage G3a)

An eGFR of 55 mL/min/1.73m² is KDIGO category G3a (45 to 59). This page explains what it means, the creatinine behind it, and what to ask next.

Medically reviewed by Dr. Rishi Kumar Kafle, MBBS, MD, FASN. Last reviewed October 2026.

Automated chemistry analyzer processing blood samples in a hospital laboratory
Laboratories report eGFR from serum creatinine with the CKD-EPI equation. Illustrative image.

An eGFR of 55 mL/min/1.73m² falls in KDIGO category G3a (45 to 59), which means mildly to moderately decreased filtration. At age 50 it matches a creatinine of about 1.53 mg/dL in a man and 1.20 mg/dL in a woman. Below 60 for more than three months meets the KDIGO definition of chronic kidney disease even without albuminuria, so a repeat test is needed to confirm it.

Where 55 Sits Within G3a

An eGFR of 55 is 10 points above the G3a floor of 45. It is 5 points below the G2 line at 60. The KDIGO categories run from G1 to G5; G3a is explained in more depth on the CKD stage 3 page.

G3a is mildly to moderately decreased filtration. If it lasts more than three months it meets the definition of chronic kidney disease on its own, even without albuminuria. Most people have no symptoms at this level; care usually centres on blood pressure, blood glucose, a urine albumin test and a review of medicines.

What Creatinine Gives an eGFR of 55?

The creatinine behind an eGFR of 55 comes from solving the race-free CKD-EPI 2021 equation backwards, by age and sex:

Serum creatinine that gives an eGFR of 55 (CKD-EPI 2021)
AgeManWoman
301.70 mg/dL (150 µmol/L)1.33 mg/dL (118 µmol/L)
401.61 mg/dL (143 µmol/L)1.27 mg/dL (112 µmol/L)
501.53 mg/dL (135 µmol/L)1.20 mg/dL (106 µmol/L)
601.45 mg/dL (129 µmol/L)1.14 mg/dL (101 µmol/L)
701.38 mg/dL (122 µmol/L)1.08 mg/dL (96 µmol/L)
851.28 mg/dL (113 µmol/L)1.00 mg/dL (89 µmol/L)

A 30-year-old man reaches 55 at 1.70 mg/dL, while an 85-year-old woman reaches it at 1.00 mg/dL. The older the person, the lower the creatinine behind the same eGFR. Nearby creatinine guides: creatinine 1.2 mg/dL (106 µmol/L), creatinine 1.3 mg/dL (115 µmol/L), creatinine 1.4 mg/dL (124 µmol/L), creatinine 1.6 mg/dL (141 µmol/L), creatinine 1.7 mg/dL (150 µmol/L).

eGFR 55 in Absolute mL/min

eGFR is indexed to a body surface area (BSA) of 1.73m². To compare it with a creatinine clearance, or for a very small or large adult, it can be de-indexed with eGFR × BSA ÷ 1.73. For an eGFR of 55, the absolute values are:

eGFR 55 de-indexed with Mosteller BSA
Example adultBSA (m²)Absolute GFR (mL/min)
Man, 40, 178 cm, 80 kg1.9963
Woman, 65, 163 cm, 62 kg1.6753
Woman, 82, 157 cm, 48 kg1.4546
Man, 55, 175 cm, 118 kg2.4076

What Changes at an eGFR of 55

55 is 25 points above 30, and a fall of about 47% would cross that line. Below 30, KDIGO advises sharing care with a kidney specialist (nephrologist). It is already below 60.

1 of the 9 medicines in our registry whose labels use eGFR have a rule in force at 55. Compared with an eGFR of 60, one rule starts by 55: glyburide (avoid (CKD stage 3 to 5)).

eGFR-based label rules in our dosing registry at an eGFR of 55
MedicineAt eGFR 55Next change if eGFR falls
Metforminno eGFR rule in forceat 45 or lower: not to be started; the registry advises halving an existing dose
Sitagliptinno eGFR rule in forceat 44 or lower: dose lowered to 50 mg
Saxagliptinno eGFR rule in forceat 45 or lower: dose lowered to 2.5 mg
Dapagliflozinno eGFR rule in forceat 44 or lower: glucose-lowering effect limited
Empagliflozinno eGFR rule in forceat 29 or lower: glucose-lowering effect limited; other uses follow the indication
Canagliflozinno eGFR rule in forceat 29 or lower: use limited; depends on the indication
Spironolactoneno eGFR rule in forceat 29 or lower: avoid
Hydrochlorothiazideno eGFR rule in forceat 29 or lower: ineffective; the registry suggests a loop diuretic instead
Glyburideavoid (CKD stage 3 to 5)none lower in the registry

These rows restate our renal dosing registry, which summarises the drug labels. Check the current label and the indication; the prescriber makes the dose decision.

Drug Dosing Cutoffs at eGFR 55

No drug in our renal dosing registry has a label cutoff at exactly 55.

The nearest other cutoffs are up at 60 (9 drugs, listed under eGFR 60) and down at 50 (16 drugs, listed under eGFR 50). Always confirm the current label, and leave the dose decision to the prescriber.

How a Result of 55 Is Confirmed

A result of 55 is confirmed by repeat testing over time, because one eGFR is a snapshot that can dip with dehydration or illness. Chronic kidney disease is diagnosed only when a low result, or kidney damage, lasts more than three months. Repeat testing, a urine albumin-to-creatinine ratio and, where muscle mass misleads, cystatin C confirm it.

When to Talk to Your Clinician

Bring an eGFR of 55 to your next appointment rather than waiting for symptoms. A repeat test in about three months, a urine albumin check and a medication review are the usual next steps. Seek timely advice for swelling, a marked drop in urine output or new breathlessness, and have kidney function rechecked before and after any scan that uses contrast dye.

Nearby eGFR Results

Or browse all eGFR results. For drug dosing, your clinician may use a creatinine clearance rather than eGFR (see CrCl vs eGFR).

Frequently Asked Questions

What does an eGFR of 55 mean?

An eGFR of 55 mL/min/1.73m² is KDIGO category G3a (45 to 59), mildly to moderately decreased. An eGFR of 55 is 10 points above the G3a floor of 45. It is 5 points below the G2 line at 60. Confirm it with a repeat test before drawing conclusions.

What creatinine gives an eGFR of 55?

With CKD-EPI 2021, a 50-year-old man has an eGFR of 55 at a creatinine of about 1.53 mg/dL (135 µmol/L), and a 50-year-old woman at about 1.20 mg/dL (106 µmol/L). Older adults reach it at lower creatinine values.

References

  1. National Kidney Foundation. How to Classify CKD (GFR and albuminuria categories).
  2. Kidney Disease: Improving Global Outcomes (KDIGO). KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of CKD.
  3. Inker LA, Eneanya ND, Coresh J, et al. New creatinine- and cystatin C-based equations to estimate GFR without race. N Engl J Med. 2021;385(19):1737-1749.
  4. MedlinePlus (NIH). Glomerular Filtration Rate (GFR) Test.
  5. DailyMed (U.S. National Library of Medicine). FDA drug labeling.

Medical review by Dr. Rishi Kumar Kafle

MBBS, MD, FASN, Consultant Nephrologist

Nepal Mediciti, Kathmandu

Last reviewed October 2026. The reviewer checks equation use, normal ranges, CKD cutoffs and renal dosing thresholds against current guidance before a page is presented as authoritative.